| Titre : | Cancer cytogenetics : Chromosomal and molecular genetic aberrations of tumor cells |
| Auteurs : | Heim Sverre |
| Type de document : | texte imprimé |
| Mention d'édition : | 04 ed. |
| Editeur : | USA (USA) : Wiley Blackwell, 2015 |
| ISBN/ISSN/EAN : | 978-1-118-79553-8 |
| Format : | 632 p. |
| Note générale : | Includes bibliographical references and index. |
| Langues: | Anglais |
| Langues originales: | Anglais |
| Index. décimale : | 616.99 (Tumeurs et maladies diverses) |
| Mots-clés: | Cancer Genetic aspects;Neoplasms genetics;Chromosome Disorders genetics;Cytogenetics methods |
| Résumé : |
-The first three editions of this acclaimed book presented a much?needed conceptual synthesis of this rapidly moving field. Now, Cancer Cytogenetics, Fourth Edition, offers a comprehensive, expanded, and up?to?date review of recent dramatic advances in this area, incorporating a vast amount of new data from the latest basic and clinical investigations. -New contributors reflecting broader international authorship and even greater expertise Greater emphasis throughout on the clinical importance and application of information about cytogenetic and molecular aberrations Includes a complete coverage of chromosome aberrations in cancer based on an assessment of the 60,000 neoplasms cytogenetically investigated to date Now produced in full color for enhanced clarity Covers how molecular genetic data (PCR?based and sequencing information) are collated with the cytogenetic data where pertinent Discusses how molecular cytogenetic data (based on studies using FISH, CGH, SNP, etc) are fused with karyotyping data to enable an as comprehensive understanding of cancer cytogenetics as is currently possible Over the last four decades, cancer cytogenetics has become widely recognized both as a basic research tool for investigations of tumor biology and a clinical methodology providing vital insights into cancer development and progression. The first three editions of this acclaimed book presented a much?needed conceptual synthesis of this rapidly moving field. Now, Cancer Cytogenetics, Fourth Edition, offers a comprehensive, expanded, and up?to?date review of recent dramatic advances in this area, incorporating a vast amount of new data from the latest basic and clinical investigations. -Edited by two leading experts, and now involving an expanded panel of international experts, the book offers an authoritative description of neoplastic processes at the chromosomal level of genomic organization. Now in full color, Cancer Cytogenetics, Fourth Edition; -Includes a complete coverage of chromosome aberrations in cancer based on an assessment of the 60,000 neoplasms cytogenetically investigated to date, Offers greater emphasis throughout on the clinical importance and application of information about cytogenetic and molecular aberrations, Covers how molecular genetic data (PCR?based and sequencing information) are collated with the cytogenetic data where pertinent, Discusses how molecular cytogenetic data (based on studies using FISH, CGH, SNP, etc) are fused with karyotyping data to enable an as comprehensive understanding of cancer cytogenetics as is currently possible. -Cancer researchers, clinical oncologists, geneticists, and especially anyone interested in the translational aspects of bench?to?bedside research in cancer genetics will find this new edition indispensable as a reference and clinical tool. |
| Note de contenu : |
Table of contents: Contributors vii Preface to the Fourth Edition ix 1 How it all began: cancer cytogenetics before sequencing 1 Felix Mitelman and Sverre Heim 2 Cytogenetic methods 11 David Gisselsson 3 Cytogenetic nomenclature 19 Sverre Heim and Felix Mitelman 4 Nonrandom chromosome abnormalities in cancer: an overview 26 Sverre Heim and Felix Mitelman 5 From chromosomes to genes: searching for pathogenetic fusions in cancer 42 Ioannis Panagopoulos 6 Acute myeloid leukemia 62 Bertil Johansson and Christine J. Harrison 7 Myelodysplastic syndromes 126 Harold J. Olney and Michelle M. Le Beau 8 Chronic myeloid leukemia 153 Thoas Fioretos 9 Chronic myeloproliferative neoplasms 175 Peter Vandenberghe and Lucienne Michaux 10 Acute lymphoblastic leukemia 198 Christine J. Harrison and Bertil Johansson 11 Mature B] and T]cell neoplasms and Hodgkin lymphoma 252 Reiner Siebert and Sietse M. Aukema 12 Tumors of the upper aerodigestive tract 332 Susanne M. Golli 13 Tumors of the lung 361 Penny Nymark, Eeva Kettunen and Sakari Knuutila 14 Tumors of the digestive tract 373 Georgia Bardi and Sverre Heim 15 Tumors of the urinary tract 401 Paola Dal Cin 16 Tumors of the breast 426 Manuel R. Teixeira, Nikos Pandis and Sverre Heim 17 Tumors of the female genital organs 447 Francesca Micci and Sverre Heim 18 Tumors of the male genital organs 481 Manuel R. Teixeira and Sverre Heim 19 Tumors of endocrine glands 497 Jörn Bullerdiek and David Gisselsson 20 Tumors of the nervous system 515 Petter Brandal and Sverre Heim 21 Tumors of the eye 538 Karen Sisley 22 Tumors of the skin 555 Fredrik Mertens, Felix Mitelman and Sverre Heim 23 Tumors of bone 566 Fredrik Mertens and Nils Mandahl 24 Soft tissue tumors 583 Nils Mandahl and Fredrik Mertens Index 615 |
| En ligne : | https://www.amazon.fr/Cancer-Cytogenetics-Chromosomal-Molecular-Aberrations/dp/1118795539/ref=sr_1_1?__mk_fr_FR=%C3%85M%C3%85%C5%BD%C3%95%C3%91&dchild=1&keywords=9781118795538&qid=1614258589&sr=8-1#reader_1118795539 |
Exemplaires
| Code-barres | Cote | Support | Localisation | Section | Disponibilité |
|---|---|---|---|---|---|
| M037596 | M5010 | Livre | Salle de consultation sur place | Livres Anglais | Exclu du prêt |
| M038606 | M5010 | Livre | Salle de prêt | Livres Français | Disponible |
